Description

2,3-Difluoro-4-Methylphenylboronic acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, as well as in advanced materials science for creating novel electronic and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, leveraging the fluorine atoms to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the difluoro-methylphenyl moiety contributes to biological activity and environmental persistence profiles.
• Material Science: Serves as a monomer or precursor in the production of specialty polymers, liquid crystals, and organic electronic materials (OLEDs, OFETs).
• Chemical Research & Development: Employed in academic and industrial R&D for method development and library synthesis in medicinal and process chemistry.
• Ligand & Catalyst Preparation: Utilized to synthesize sophisticated boronic ester ligands and catalysts for asymmetric synthesis and other catalytic transformations.

Basic Information

Product Name	2,3-Difluoro-4-Methylphenylboronic acid
CAS No.	508235-16-3
Molecular Formula	C7H7BF2O2
Molecular Weight	171.94 g/mol
Synonyms	(2,3-Difluoro-4-methylphenyl)boronic acid; 2,3-Difluoro-p-tolylboronic acid; 4-Methyl-2,3-difluorophenylboronic acid; B-(2,3-Difluoro-4-methylphenyl)boronic acid; 508235-16-3; 2,3-Difluoro-4-methylbenzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2,3-Difluoro-4-Methylphenylboronic acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling reactions. A Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), identity confirmation, and impurity profiles is supplied with each shipment to guarantee consistency and reliability for your processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.