Description

(-)-2,3-Bis[(2R,5R)-2,5-Dimethylphospholanyl]Maleic Anhydride is a high-value, chiral phosphine ligand precursor used in asymmetric catalysis. This compound matters for its ability to form highly selective metal complexes, enabling the synthesis of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel synthetic routes.

Application

• As a precursor for the synthesis of chiral phosphine ligands in homogeneous asymmetric hydrogenation.
• Catalyst development for enantioselective carbon-carbon and carbon-heteroatom bond-forming reactions.
• Research and development of novel catalytic systems for pharmaceutical intermediate synthesis.
• Production of high-value chiral building blocks for active pharmaceutical ingredients (APIs).
• Use in academic and industrial research focused on organometallic chemistry and catalysis.
• Potential application in the synthesis of advanced materials requiring chiral induction.

Basic Information

Product Name	(-)-2,3-Bis[(2R,5R)-2,5-Dimethylphospholanyl]Maleic Anhydride
CAS No.	505092-86-4
Molecular Formula	C18H28O3P2
Molecular Weight	354.36 g/mol
Synonyms	(-)-2,3-Bis[(2R,5R)-2,5-dimethylphospholano]maleic anhydride; (R,R)-2,3-Bis(2,5-dimethylphospholano)maleic anhydride; (R,R)-DIMOP-MA; DIMOP-Maleic Anhydride; (R,R)-DIMOP Maleic Anhydride; (2R,5R)-2,5-Dimethylphospholane-Maleic Anhydride Adduct; Chiral Phospholane-Maleic Anhydride Ligand Precursor
EINECS	Contact for details

Quality Control

Our (-)-2,3-Bis[(2R,5R)-2,5-Dimethylphospholanyl]Maleic Anhydride is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and chiral analysis. Certificates of Analysis (COA) with detailed specifications are provided to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and easily oxidized; handle and store accordingly to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (ee)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.