Description

3-Fluoro-4-Methoxycarbonylphenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific fluorinated aromatic motifs.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs, where the boronic acid group facilitates precise molecular assembly.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors that leverage boronic acid-diol interactions for detection applications.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	3-Fluoro-4-Methoxycarbonylphenylboronic Acid
CAS No.	505083-04-5
Molecular Formula	C8H8BFO4
Molecular Weight	197.96 g/mol
Synonyms	(3-Fluoro-4-(methoxycarbonyl)phenyl)boronic acid; 4-Borono-2-fluoro-benzoic acid methyl ester; Methyl 3-fluoro-4-boronobenzoate; 2-Fluoro-4-(methoxycarbonyl)benzeneboronic acid; 3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid; Methyl 4-borono-3-fluorobenzoate; 3-Fluoro-4-methoxycarbonylbenzeneboronic Acid; 4-Methoxycarbonyl-3-fluorophenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Methoxycarbonylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are available upon request for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.