Description

Carbamic Acid, (1R,5S,6R)-Bicyclo[3.1.0]Hex-2-En-6-Yl-, 1,1-Dimethylethyl is a high-purity, advanced pharmaceutical intermediate characterized by its unique bicyclic structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of proprietary drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic compounds.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct complex molecular architectures due to its defined stereochemistry.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Carbamic Acid, (1R,5S,6R)-Bicyclo[3.1.0]Hex-2-En-6-Yl-, 1,1-Dimethylethyl
CAS No.	504437-99-4
Molecular Formula	C12H19NO2
Molecular Weight	209.29 g/mol
Synonyms	(1R,5S,6R)-6-(tert-Butoxycarbonylamino)bicyclo[3.1.0]hex-2-ene; N-Boc-(1R,5S,6R)-6-Aminobicyclo[3.1.0]hex-2-ene; tert-Butyl (1R,5S,6R)-bicyclo[3.1.0]hex-2-en-6-ylcarbamate; (1R,5S,6R)-Bicyclo[3.1.0]hex-2-en-6-amine, N-Boc-protected; Bicyclo[3.1.0]hex-2-ene-6-carbamic acid tert-butyl ester (stereospecific); Boc-protected bicyclo[3.1.0]hexenylamine
EINECS	Contact for details

Quality Control

Every batch of Carbamic Acid, (1R,5S,6R)-Bicyclo[3.1.0]Hex-2-En-6-Yl-, 1,1-Dimethylethyl is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, meeting the exacting standards required for pharmaceutical R&D and pre-clinical development. A detailed Certificate of Analysis (COA) with supporting chromatographic and spectroscopic data (HPLC, GC, NMR) is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.