Description

4-Fluoro-trans-β-Styrylboro is a specialized organoboron compound, specifically a trans-configured styrylboronic acid derivative. This chemical matters as a versatile and valuable building block in modern synthetic organic chemistry, particularly for cross-coupling reactions. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel fluorinated drug candidates, including kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in the development of new fluorinated pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of fluorinated organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for studying biological processes and protein interactions.
• Catalyst Ligand Development: Acts as a starting material for synthesizing novel bidentate or monodentate ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring high-purity, fluorinated boronic acid derivatives.

Basic Information

Product Name	4-Fluoro-trans-β-Styrylboro
CAS No.	504433-86-7
Molecular Formula	C8H8BFO2
Molecular Weight	165.96 g/mol
Synonyms	trans-4-Fluorostyrylboronic Acid; (E)-4-Fluorostyrylboronic Acid; (E)-2-(4-Fluorophenyl)ethenylboronic Acid; 4-Fluoro-trans-Styrylboronic Acid; 4-Fluoro-β-Styrylboronic Acid; B-(trans-2-(4-Fluorophenyl)ethenyl)boronic Acid; 4-Fluoro-trans-Cinnamylboronic Acid; (E)-4-Fluorovinylbenzeneboronic Acid
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-trans-β-Styrylboro is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive cross-coupling applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, isomeric ratio, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (trans-isomer, HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.