Description

Difluoro-(3-Methyl-Pyridin-2-Yl)-Acetic Acid Ethyl Ester is a high-purity fluorinated pyridine derivative, a crucial building block in modern synthetic chemistry. This compound is valued for its unique molecular structure, which enables the introduction of difluoroacetate and pyridine motifs into complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, including potential drug candidates and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorinated pyridine core can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of novel fluorinated organic materials and liquid crystals.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific fluorinated heterocyclic architectures.

Basic Information

Product Name	Difluoro-(3-Methyl-Pyridin-2-Yl)-Acetic Acid Ethyl Ester
CAS No.	503627-61-0
Molecular Formula	C10H11F2NO2
Molecular Weight	215.20 g/mol
Synonyms	Ethyl 2,2-Difluoro-2-(3-methylpyridin-2-yl)acetate; 2,2-Difluoro-2-(3-methyl-2-pyridinyl)acetic Acid Ethyl Ester; Ethyl [Difluoro(3-methyl-2-pyridinyl)methyl]acetate; Difluoro(3-methyl-2-pyridinyl)acetic Acid Ethyl Ester; 503627-61-0; Ethyl α,α-Difluoro-α-(3-methyl-2-pyridyl)acetate
EINECS	Contact for details

Quality Control

Our Difluoro-(3-Methyl-Pyridin-2-Yl)-Acetic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.