Description

(R)-Binaphthylisobutylphosphite is a chiral organophosphorus compound of significant interest in asymmetric synthesis. Its primary value lies in its utility as a versatile ligand and catalyst precursor for a wide range of metal-catalyzed reactions, enabling the production of enantiomerically pure compounds. This high-purity specialty chemical is essential for research and development laboratories, as well as production facilities in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel chiral molecules.

Application

• As a chiral ligand in transition metal catalysis for asymmetric hydrogenation and carbon-carbon bond-forming reactions.
• As a precursor for synthesizing novel chiral phosphine-phosphite hybrid ligands with tailored properties.
• In the development of enantioselective catalysts for pharmaceutical intermediate synthesis.
• For research into new methodologies in asymmetric synthesis within academic and industrial R&D settings.
• Potential use in the synthesis of chiral agrochemicals and flavors/fragrances.
• As a standard or reference material for analytical method development in chiral analysis.

Basic Information

Product Name	(R)-Binaphthylisobutylphosphite
CAS No.	503544-55-6
Molecular Formula	C28H27O2P
Molecular Weight	426.48 g/mol
Synonyms	(R)-2,2'-Bis(diisobutylphosphino)-1,1'-binaphthyl; (R)-BINAP-iBu; (R)-2,2'-Bis(diisobutylphosphanyl)-1,1'-binaphthyl; (R)-BINAP(Di-i-Bu); (R)-BINAP-i-Bu; (R)-BINAP(diisobutyl); (R)-1,1'-Binaphthalene-2,2'-diylbis(diisobutylphosphine); (R)-BINAP-type iBu ligand
EINECS	Contact for details

Quality Control

Our (R)-Binaphthylisobutylphosphite is manufactured under strict quality control protocols to ensure high chemical and enantiomeric purity, critical for catalytic performance. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and identity is provided with every shipment to guarantee consistency and support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at room temperature (15-25°C). This material is moisture-sensitive and easily oxidized; prolonged exposure to air or moisture should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.