Description

R-(+)-6,6'-Bis(Diphenylphosphino)-2,2',3,3'-Tetrahydro-5,5'-Bi-1,4-Benzodioxin CAS NO 503538-68-9 is a high-value, chiral bidentate phosphine ligand essential for asymmetric catalysis. This compound matters because it enables the precise control of stereochemistry in the synthesis of complex pharmaceutical intermediates and fine chemicals. It is critically needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel synthetic routes with high enantioselectivity and yield.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for pharmaceutical active ingredient (API) synthesis.
• Critical component in rhodium- and ruthenium-catalyzed processes for producing enantiomerically pure compounds.
• Used in the asymmetric synthesis of amino acids, alcohols, and other chiral building blocks.
• Facilitates cross-coupling reactions where stereochemical control is paramount.
• Employed in academic and industrial research for developing new catalytic methodologies.
• Applicable in the scale-up production of specialty chemicals requiring high optical purity.

Basic Information

Product Name	R-(+)-6,6'-Bis(Diphenylphosphino)-2,2',3,3'-Tetrahydro-5,5'-Bi-1,4-Benzodioxin
CAS No.	503538-68-9
Molecular Formula	C40H32O4P2
Molecular Weight	638.62 g/mol
Synonyms	(R)-(+)-2,2'-Bis(Diphenylphosphino)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthyl-4,4'-Diyl Diethyl Ether; (R)-H8-BINAP(OEt)2; (R)-H8-BINAP(OEt)2; (R)-H8-BINAP Diethyl Ether; (R)-OctahydroBINAP Diethyl Ether; (R)-O-BINAP; (R)-6,6'-Bis(diphenylphosphino)-2,2',3,3'-tetrahydro-5,5'-bi-1,4-benzodioxin; (R)-DTBM-SEGPHOS (related class)
EINECS	Contact for details

Quality Control

Every batch of our R-(+)-6,6'-Bis(Diphenylphosphino)-2,2',3,3'-Tetrahydro-5,5'-Bi-1,4-Benzodioxin is produced and tested under strict quality management systems to ensure high chemical purity and chiral integrity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. This product is easily oxidized and light-sensitive. The storage area should be cool, dry, and well-ventilated. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.