Description

tert-Butyl 4-Chloro-3-Nitrophenylcarbamate is a high-purity chemical intermediate characterized by its carbamate-protected aniline structure with chloro and nitro substituents. This compound is valued for its role as a critical building block in the synthesis of complex organic molecules, particularly in pharmaceutical research and development. It is primarily sought after by fine chemical manufacturers and R&D laboratories engaged in creating active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides, fungicides, and insecticides, leveraging its halogenated nitroaromatic core.
• Organic Synthesis Reagent: Used in academic and industrial research laboratories for constructing complex heterocycles and functionalized aromatic compounds.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials requiring specific aromatic monomers.
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes and inhibitors to study biological pathways.

Basic Information

Product Name	tert-Butyl 4-Chloro-3-Nitrophenylcarbamate
CAS No.	503524-47-8
Molecular Formula	C11H13ClN2O4
Molecular Weight	272.69 g/mol
Synonyms	tert-Butyl N-(4-Chloro-3-nitrophenyl)carbamate; 4-Chloro-3-nitroaniline, N-BOC protected; BOC-4-Chloro-3-nitroaniline; N-Boc-4-Chloro-3-nitroaniline; N-(tert-Butoxycarbonyl)-4-chloro-3-nitroaniline; 1-(tert-Butoxycarbonylamino)-4-chloro-3-nitrobenzene; tert-Butyl (4-chloro-3-nitrophenyl)carbamate; Carbamic acid, N-(4-chloro-3-nitrophenyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Chloro-3-Nitrophenylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.