Description

2-Fluoro-4-Trifluoromethoxybenzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials development. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and liquid crystal industries seeking to synthesize complex fluorinated aromatic structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethoxy and fluorine substituents for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the fluorinated aromatic core contributes to efficacy and environmental persistence profiles.
• Material Science: Serves as a monomer or building block for advanced polymers, organic semiconductors, and liquid crystal materials requiring specific electronic and steric properties.
• Chemical Research & Development: Employed in academic and industrial R&D for constructing diverse compound libraries and exploring new synthetic methodologies via palladium-catalyzed cross-coupling.
• Diagnostic Reagent Manufacturing: Potential use in synthesizing probes and labeling agents for biochemical assays and medical diagnostics.

Basic Information

Product Name	2-Fluoro-4-Trifluoromethoxybenzeneboronic Acid
CAS No.	503309-10-2
Molecular Formula	C7H5BF4O3
Molecular Weight	223.92 g/mol
Synonyms	(2-Fluoro-4-(trifluoromethoxy)phenyl)boronic acid; 2-Fluoro-4-(trifluoromethoxy)benzeneboronic acid; 2-Fluoro-4-trifluoromethoxybenzeneboronic acid; 4-Trifluoromethoxy-2-fluorophenylboronic acid; B-[2-Fluoro-4-(trifluoromethoxy)phenyl]boronic acid; 2-Fluoro-4-trifluoromethoxy phenylboronic acid; 503309-10-2
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Trifluoromethoxybenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.