Description

Bicyclo[2.2.2]Octanone, 4-Fluoro-1-Methyl- (9Ci) is a high-purity, fluorinated bicyclic ketone building block of significant interest in advanced organic synthesis. Its unique, rigid three-dimensional structure and fluorine substituent make it a valuable intermediate for creating novel compounds with tailored properties. This product is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require sophisticated scaffolds for drug discovery and specialty chemical development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disease targets, where the fluorine atom and rigid core can enhance bioavailability and binding affinity.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom's ability to improve metabolic stability and membrane permeability in active compounds.
• Ligand & Catalyst Development: Acts as a precursor for chiral ligands or as a structural component in organocatalysts, useful in asymmetric synthesis for producing enantiomerically pure compounds.
• Advanced Materials Synthesis: Employed in the creation of specialty polymers, liquid crystals, or organic electronic materials, where the bicyclic framework contributes to thermal stability and specific optical properties.
• Chemical Biology & Probe Design: Utilized as a scaffold for developing molecular probes and bio-conjugation tools, taking advantage of its potential for further functionalization.
• Flavor & Fragrance Chemistry: May be investigated as an intermediate for synthesizing novel aroma chemicals with unique olfactory profiles due to its complex, cage-like structure.

Basic Information

Product Name	Bicyclo[2.2.2]Octanone, 4-Fluoro-1-Methyl- (9Ci)
CAS No.	502141-71-1
Molecular Formula	C9H13FO
Molecular Weight	156.20 g/mol
Synonyms	4-Fluoro-1-methylbicyclo[2.2.2]octan-2-one; 1-Methyl-4-fluorobicyclo[2.2.2]octan-2-one; 4-Fluoro-1-methyl-2-bicyclo[2.2.2]octanone; Bicyclo[2.2.2]octan-2-one, 4-fluoro-1-methyl-; Fluorinated Bicyclic Ketone; F-Methyl BCO Ketone
EINECS	Contact for details

Quality Control

Every batch of our Bicyclo[2.2.2]Octanone, 4-Fluoro-1-Methyl- (9Ci) is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay purity and identity confirmation. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical development, ensuring reliable supply and traceability for critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider maintaining the product under an inert atmosphere to preserve optimal quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.