Description

6-Fluorobenzo[B]Thiene-2-Boronic Acid is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its core value lies in enabling the efficient construction of complex molecules, particularly through Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), especially in the development of fluorinated heterocyclic compounds.
• Suzuki-Miyaura Cross-Coupling Reagent: Used as a boronic acid coupling partner to form carbon-carbon bonds, crucial for creating complex molecular architectures in drug discovery.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, and insecticides that incorporate the benzothiophene scaffold.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, light-emitting materials, and other functional organic electronic components.
• Chemical Biology & Probe Synthesis: Useful for creating fluorescent probes or labeled compounds for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production in fine chemical manufacturing.

Basic Information

Product Name	6-Fluorobenzo[B]Thiene-2-Boronic Acid
CAS No.	501944-65-6
Molecular Formula	C8H6BFO2S
Molecular Weight	195.01 g/mol
Synonyms	6-Fluorobenzo[b]thiophene-2-boronic acid; (6-Fluorobenzo[b]thiophen-2-yl)boronic acid; 6-Fluoro-1-benzothiophene-2-boronic acid; 2-Borono-6-fluorobenzo[b]thiophene; 6-Fluoro-2-benzothienylboronic acid; 6-F-BT-2-BA; 6-Fluorobenzo[b]thien-2-ylboronic acid; CAS 501944-65-6
EINECS	Contact for details

Quality Control

Our 6-Fluorobenzo[B]Thiene-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every lot to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. For long-term storage, consider storing under an inert gas in a freezer (-20°C).

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.