Description

4'-Boronic Acid-Biphenyl-4-Carboxylic Acid Methyl Ester is a high-value bifunctional organic building block containing both a boronic acid and a methyl ester group. This compound is critical for the synthesis of complex molecules via cross-coupling reactions, particularly Suzuki-Miyaura coupling. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those with biphenyl core structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific biphenyl motifs.
• Material Science: Serves as a monomer or building block for creating advanced organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysts used in asymmetric synthesis.
• Chemical Biology Research: Utilized as a probe or linker in bioconjugation chemistry and the development of biochemical tools.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke organic synthesis for clients.

Basic Information

Product Name	4'-Boronic Acid-Biphenyl-4-Carboxylic Acid Methyl Ester
CAS No.	501944-43-0
Molecular Formula	C14H13BO4
Molecular Weight	256.06 g/mol
Synonyms	4'-(Methoxycarbonyl)-[1,1'-biphenyl]-4-boronic acid; Methyl 4'-(boronic acid)-[1,1'-biphenyl]-4-carboxylate; [1,1'-Biphenyl]-4-boronic acid, 4'-(methoxycarbonyl)-; 4-Carbomethoxy-4'-boronic acid biphenyl; 4-Methoxycarbonylphenylboronic acid; Biphenyl-4-carboxylic acid methyl ester-4'-boronic acid; 4'-(Boronyl)-biphenyl-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 4'-Boronic Acid-Biphenyl-4-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.