Description

4-(Chlorocarbonyl)-2,6-Difluoroanisole is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound matters because its unique structure, featuring both an acid chloride and difluoromethoxy groups, enables precise molecular construction for demanding applications. It is primarily needed by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug molecules, particularly those requiring difluoromethoxy or benzoic acid derivative motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in display technologies.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with tailored thermal and chemical resistance.
• Organic Electronics: Employed in the synthesis of charge-transport materials or semiconducting molecules for OLEDs and other electronic devices.
• Chemical Research & Development: A versatile reagent for constructing complex aromatic systems in academic and industrial research settings.

Basic Information

Product Name	4-(Chlorocarbonyl)-2,6-Difluoroanisole
CAS No.	501701-43-5
Molecular Formula	C9H5ClF2O2
Molecular Weight	218.59 g/mol
Synonyms	2,6-Difluoro-4-(methoxycarbonyl)benzoyl chloride; 4-(Chlorocarbonyl)-2,6-difluoro-1-methoxybenzene; 2,6-Difluoroanisole-4-carbonyl chloride; 4-Carboxy-2,6-difluoroanisole chloride; Benzoic acid, 2,6-difluoro-4-methoxy-, chloride; 4-Methoxy-2,6-difluorobenzoyl chloride
EINECS	Contact for details

Quality Control

Every batch of 4-(Chlorocarbonyl)-2,6-Difluoroanisole is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) documenting all test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.