Description

5-Bromo-2-Fluoro-3-Pyridylboronic Acid is a high-value organoboron building block essential for modern cross-coupling reactions, particularly the Suzuki-Miyaura reaction. Its core value lies in enabling the precise and efficient construction of complex, fluorinated pyridine derivatives, which are privileged scaffolds in medicinal chemistry and materials science. This compound is critically needed by pharmaceutical R&D teams, agrochemical innovators, and advanced materials scientists for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated pyridine cores in drug discovery programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with enhanced activity and selectivity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Materials Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and charge-transport materials.
• Chemical Biology Probes: Useful for creating tagged molecules and probes to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs and fine chemical suppliers producing bespoke compounds for clients.

Basic Information

Product Name	5-Bromo-2-Fluoro-3-Pyridylboronic Acid
CAS No.	501435-91-2
Molecular Formula	C5H4BBrFNO2
Molecular Weight	219.80 g/mol
Synonyms	(5-Bromo-2-fluoropyridin-3-yl)boronic Acid; 3-Borono-5-bromo-2-fluoropyridine; 5-Bromo-2-fluoro-3-pyridineboronic Acid; 5-Bromo-2-fluoropyridine-3-boronic Acid; 2-Fluoro-5-bromo-3-pyridylboronic Acid; 3-Pyridineboronic acid, 5-bromo-2-fluoro-
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoro-3-Pyridylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.