Description

tert-Butyl 3,5-Dioxopiperazine-1-Carboxylate is a high-purity, protected piperazine-2,5-dione derivative serving as a critical synthetic intermediate in advanced organic synthesis. Its primary value lies in providing a versatile, reactive scaffold for constructing complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty fine chemical industries seeking to build novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those containing piperazine or diketopiperazine (DKP) cores.
• Peptidomimetic Research: Used to create constrained peptide analogs and DKP-based scaffolds for drug discovery targeting various diseases.
• Agrochemical Synthesis: Intermediate in the development of novel herbicides, fungicides, and insecticides with specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral auxiliaries and ligands used in asymmetric catalysis.
• Polymer Chemistry: Can be utilized as a monomer or cross-linking agent for specialty polymers with unique thermal or mechanical properties.
• Academic & R&D: Fundamental reagent in organic chemistry research for methodology development and exploring new heterocyclic reactions.

Basic Information

Product Name	tert-Butyl 3,5-Dioxopiperazine-1-Carboxylate
CAS No.	501127-89-5
Molecular Formula	C9H14N2O4
Molecular Weight	214.22 g/mol
Synonyms	1-Boc-2,5-diketopiperazine; 1-(tert-Butoxycarbonyl)-2,5-diketopiperazine; tert-Butyl 2,5-dioxopiperazine-1-carboxylate; 2,5-Dioxo-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1-N-Boc-2,5-diketopiperazine; Boc-DKP; Boc-2,5-DKP; 1-Boc-2,5-DKP
EINECS	Contact for details

Quality Control

Our tert-Butyl 3,5-Dioxopiperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.