Description

D-Arabino-Heptononitrile, 2,6-Anhydro-3,4-Dideoxy-5,7-Di-o-Methyl- (9Ci) is a specialized, high-purity chemical building block belonging to the class of modified sugar nitriles. This compound matters as a critical chiral intermediate for the synthesis of complex nucleoside analogs and other biologically active molecules, offering precise stereochemical control. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of antiviral agents, enzyme inhibitors, and novel carbohydrate-based therapeutics. Its unique structure makes it a valuable asset for medicinal chemistry and advanced organic synthesis programs.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of nucleoside-based antiviral and anticancer drugs.
• Medicinal Chemistry: Used in the design and synthesis of novel enzyme inhibitors and receptor ligands targeting specific biological pathways.
• Carbohydrate Chemistry Research: Serves as a sophisticated building block for constructing complex, deoxygenated sugar analogs and glycomimetics.
• Bioconjugation: Potential use in creating labeled probes or conjugates for biochemical and diagnostic applications due to its reactive nitrile group.
• Process Chemistry Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) requiring this specific stereochemistry.

Basic Information

Product Name	D-Arabino-Heptononitrile, 2,6-Anhydro-3,4-Dideoxy-5,7-Di-o-Methyl- (9Ci)
CAS No.	501101-19-5
Molecular Formula	C9H13NO4
Molecular Weight	199.20 g/mol
Synonyms	2,6-Anhydro-3,4-dideoxy-5,7-di-O-methyl-D-arabino-heptononitrile; 5,7-Di-O-methyl-2,6-anhydro-3,4-dideoxy-D-arabino-heptononitrile; D-arabino-Heptononitrile, 2,6-anhydro-3,4-dideoxy-5,7-di-O-methyl-; Modified Arabino Sugar Nitrile; 2,6-Anhydro Sugar Nitrile Derivative; CAS 501101-19-5
EINECS	Contact for details

Quality Control

Every batch of D-Arabino-Heptononitrile, 2,6-Anhydro-3,4-Dideoxy-5,7-Di-o-Methyl- (9Ci) is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development work. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), chiral purity, and impurity profile is supplied with each shipment to guarantee it meets your specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.