Description

Fmoc-(S)-3-Amino-3-(2,3-Dichloro-Phenyl)-Propionic Acid is a high-purity, non-natural amino acid derivative designed for advanced peptide synthesis. This compound is a critical chiral building block, enabling the precise introduction of a dichlorophenyl side chain into peptide sequences, which is essential for modulating biological activity and physicochemical properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and chemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected amino acid, it is a fundamental reagent for the sequential assembly of custom peptides on resin.
• Pharmaceutical Research & Development: Serves as a key intermediate in the discovery and synthesis of peptide-based drug candidates targeting various diseases.
• Peptidomimetic Design: Used to create modified peptide structures with enhanced stability, bioavailability, or receptor affinity.
• Chemical Biology: Incorporation into peptide tags or probes for studying protein-protein interactions and cellular processes.
• API Intermediate Manufacturing: Employed in the scaled-up production of active pharmaceutical ingredients (APIs) for clinical trials and commercial supply.

Basic Information

Product Name	Fmoc-(S)-3-Amino-3-(2,3-Dichloro-Phenyl)-Propionic Acid
CAS No.	501015-35-6
Molecular Formula	C24H19Cl2NO4
Molecular Weight	456.32 g/mol
Synonyms	Fmoc-3-Amino-3-(2,3-dichlorophenyl)propanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-amino-3-(2,3-dichlorophenyl)propionic acid; Fmoc-Amp(2,3-Cl2)-OH; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,3-dichlorophenyl)propanoic acid; N-α-Fmoc-3-amino-3-(2,3-dichlorophenyl)propionic acid; Fmoc-3-(2,3-dichlorophenyl)-β-alanine; Fmoc-Dcp-OH
EINECS	Contact for details

Quality Control

Our Fmoc-(S)-3-Amino-3-(2,3-Dichloro-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.