Description

Boc-(R)-3-Amino-3-(3-Nitro-Phenyl)-Propanoic Acid is a high-purity, non-natural amino acid derivative featuring a chiral center and a nitro-aromatic protecting group. This compound is a critical chiral building block for the synthesis of complex molecules, offering precise stereochemical control. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams in the development of novel active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for targeted therapies.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a non-natural, nitro-phenyl-containing amino acid residue.
• Protease Inhibitor Development: Serves as a core structure or intermediate in the design of enzyme inhibitors due to its amino acid-like properties.
• Chemical Biology Research: Employed as a molecular probe or building block in studying protein-ligand interactions and signal transduction pathways.
• Asymmetric Synthesis: Utilized as a starting material or auxiliary in catalytic asymmetric reactions to construct complex chiral molecules.
• Material Science: Potential monomer for creating specialized polymers with unique optical or electronic properties derived from the nitro-aromatic group.

Basic Information

Product Name	Boc-(R)-3-Amino-3-(3-Nitro-Phenyl)-Propanoic Acid
CAS No.	501015-24-3
Molecular Formula	C₁₄H₁₈N₂O₆
Molecular Weight	310.30 g/mol
Synonyms	(R)-3-((tert-Butoxycarbonyl)amino)-3-(3-nitrophenyl)propanoic acid; (R)-3-(Boc-amino)-3-(3-nitrophenyl)propionic acid; Boc-D-3-Amino-3-(3-nitrophenyl)propanoic acid; tert-Butyl (R)-3-amino-3-(3-nitrophenyl)propanoate (related ester); BOC-3-Amino-3-(3-nitrophenyl)propanoic Acid; (R)-N-Boc-3-Amino-3-(3-nitrophenyl)propanoic Acid; 3-(3-Nitrophenyl)-3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
EINECS	Contact for details

Quality Control

Our Boc-(R)-3-Amino-3-(3-Nitro-Phenyl)-Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and pharmaceutical-grade standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.