Description

(S)-Boc-3-(2-Naphthyl)-β-Ala-Oh is a high-purity, chiral amino acid derivative used as a critical building block in advanced organic synthesis. Its value lies in providing a protected, enantiomerically pure intermediate essential for constructing complex molecules with defined stereochemistry. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of peptide-based therapeutics, enzyme inhibitors, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs) and peptide drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a naphthylalanine derivative with a protected amine group.
• Chemical Biology Research: Employed in the study of protein-protein interactions and the development of enzyme inhibitors or receptor modulators.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to create enantiomerically enriched compounds.
• Proteomics & Bioconjugation: Useful for creating labeled peptides or peptide conjugates for diagnostic and research applications.

Basic Information

Product Name	(S)-Boc-3-(2-Naphthyl)-β-Ala-Oh
CAS No.	500770-69-4
Molecular Formula	C₁₈H₂₁NO₄
Molecular Weight	315.36 g/mol
Synonyms	(S)-3-(2-Naphthyl)-β-alanine, N-Boc derivative; (S)-3-(Naphthalen-2-yl)-3-aminopropanoic acid tert-butyl ester; N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-L-β-alanine; Boc-3-(2-Naphthyl)-L-β-Ala-OH; (S)-tert-Butyl 3-amino-3-(naphthalen-2-yl)propanoate; Boc-β-(2-Naphthyl)-L-alanine; (S)-Boc-3-(2-Naphthyl)-β-alanine
EINECS	Contact for details

Quality Control

Our (S)-Boc-3-(2-Naphthyl)-β-Ala-Oh is manufactured under strict quality control protocols to ensure high chemical purity and chiral integrity, suitable for demanding research and development applications. Each batch is analyzed via HPLC, NMR, and optical rotation to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.