Description

Cyclo (-Rgdfk) 2,2,2-Trifluoroacetic Acid is a specialized fluorinated organic acid derivative, identified by CAS NO 500577-51-5. This compound is valued for its unique structural features, which impart distinct reactivity and properties compared to standard trifluoroacetic acid, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecular architectures, particularly in the synthesis of novel active ingredients and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, especially those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Advanced Material Precursor: Serves as a monomer or modifying agent in the development of specialty polymers, coatings, and electronic materials with specific chemical resistance or surface properties.
• Organic Synthesis Reagent: Employed as a potent acid catalyst or a source of the trifluoroacetyl group in various organic transformations, including esterifications and acylations in sensitive synthetic pathways.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	Cyclo (-Rgdfk) 2,2,2-Trifluoroacetic Acid
CAS No.	500577-51-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cyclo-Rgdfk Trifluoroacetic Acid; 2,2,2-Trifluoroacetic Acid Cyclo (-Rgdfk) derivative; Cyclic Trifluoroacetic Acid derivative; TFA Cyclo-Rgdfk analog; Fluorinated Cyclic Acid Intermediate; Cycloalkyl Trifluoroacetate Acid; Specialty Fluorinated Building Block
EINECS	Contact for details

Quality Control

Our Cyclo (-Rgdfk) 2,2,2-Trifluoroacetic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency, meeting the stringent requirements for advanced chemical synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.