Description

1-[4-(Trifluoromethyl)Phenyl]Methanesulfonamide is a specialized aromatic sulfonamide derivative featuring a trifluoromethyl substituent, a structural motif of significant interest in advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active ingredients. It is primarily utilized by research institutions and industrial manufacturers engaged in the creation of agrochemicals, pharmaceuticals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting inflammation, metabolic disorders, and central nervous system (CNS) diseases.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides, leveraging the biological activity of the sulfonamide and trifluoromethyl groups.
• Material Science: Employed in the research and production of advanced polymers, liquid crystals, and other functional materials where its aromatic and fluorinated structure imparts specific properties.
• Organic Synthesis: Serves as a versatile reagent for constructing complex molecular architectures in medicinal chemistry and process development laboratories.
• Biochemical Tool Compound: Potential use in biochemical assays and as a probe for studying enzyme inhibition, particularly involving sulfonamide-binding proteins.

Basic Information

Product Name	1-[4-(Trifluoromethyl)Phenyl]Methanesulfonamide
CAS No.	500108-07-6
Molecular Formula	C8H8F3NO2S
Molecular Weight	239.21 g/mol
Synonyms	4-(Trifluoromethyl)benzenemethanesulfonamide; [4-(Trifluoromethyl)phenyl]methanesulfonamide; α-Toluenesulfonamide, 4-(trifluoromethyl)-; NSC 405124; 1-[(4-Trifluoromethyl)phenyl]methanesulfonamide; p-(Trifluoromethyl)benzylsulfonamide; 4-(Trifluoromethyl)benzylsulfonamide
EINECS	Contact for details

Quality Control

Our 1-[4-(Trifluoromethyl)Phenyl]Methanesulfonamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.