Description

(4-Fluorophenyl)Methanesulfonamide CAS NO 500108-01-0 is a specialized organosulfur compound featuring a fluorinated aromatic ring, serving as a crucial sulfonamide-based building block in advanced chemical synthesis. Its value lies in its role as a versatile intermediate for constructing more complex molecules with tailored biological or material properties. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for their development pipelines.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atom and sulfonamide group contribute to enhanced bioactivity and environmental stability.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and polar functional groups.
• Chemical Biology Probe Development: Serves as a scaffold for creating enzyme inhibitors or molecular probes to study biological pathways, leveraging its ability to mimic natural substrates.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	(4-Fluorophenyl)Methanesulfonamide
CAS No.	500108-01-0
Molecular Formula	C7H8FNO2S
Molecular Weight	189.21 g/mol
Synonyms	4-Fluorobenzenemethanesulfonamide; N-(4-Fluorophenyl)methanesulfonamide; p-Fluorophenylmethanesulfonamide; 1-(4-Fluorophenyl)methanesulfonamide; 4-Fluoro-α-toluenesulfonamide; (p-Fluorophenyl)methanesulfonamide; Methanesulfonamide, N-(4-fluorophenyl)-; 4-Fluorobenzylsulfonamide
EINECS	Contact for details

Quality Control

Our (4-Fluorophenyl)Methanesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.