Description

N2-[(Dimethylamino)Methylene]-N5-[[[(Dimethylamino)Methylene]Amino]Carbonyl]-L-Ornithine Methyl Ester is a protected ornithine derivative, a crucial building block in advanced organic synthesis. This compound is valued for its role in facilitating complex peptide coupling and protecting group strategies, ensuring high-purity intermediate formation. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel peptides, peptidomimetics, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key protected amino acid derivative in the multi-step synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a specialized building block for incorporating ornithine residues with orthogonal protecting groups.
• Bioconjugation Chemistry: Serves as a precursor for creating linkers or functional handles in antibody-drug conjugates (ADCs) and other bioconjugation applications.
• Research & Development: Essential for academic and industrial R&D in medicinal chemistry for exploring new structures in drug discovery programs.
• Protecting Group Strategy: Utilized in synthetic routes where selective protection and deprotection of amino and carboxyl groups are required.

Basic Information

Item	Details
Product Name	N2-[(Dimethylamino)Methylene]-N5-[[[(Dimethylamino)Methylene]Amino]Carbonyl]-L-Ornithine Methyl Ester
CAS No.	59824-38-3
Molecular Formula	C13H25N5O3
Molecular Weight	299.37 g/mol
Synonyms	Nδ-[(Dimethylamino)methylene]-Nω-[[[(dimethylamino)methylene]amino]carbonyl]-L-ornithine methyl ester; L-Ornithine, N2-[(dimethylamino)methylene]-N5-[[[(dimethylamino)methylene]amino]carbonyl]-, methyl ester; Methyl N2-[(dimethylamino)methylene]-N5-[[[(dimethylamino)methylene]amino]carbonyl]-L-ornithinate; Protected L-Ornithine derivative; Ornithine(DMF)2-OMe
EINECS	Contact for details

Quality Control

Our N2-[(Dimethylamino)Methylene]-N5-[[[(Dimethylamino)Methylene]Amino]Carbonyl]-L-Ornithine Methyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.