Description

Pancreatic Polypeptide, Human is a 36-amino acid peptide hormone produced by the pancreatic islets. This compound is a critical research tool for studying endocrine physiology, appetite regulation, and metabolic disorders. It is essential for researchers and developers in the pharmaceutical and life science sectors focusing on diabetes, obesity, and gastrointestinal function.

Application

• Biomedical Research: Fundamental studies on pancreatic endocrine function and hormone secretion mechanisms.
• Metabolic Disorder Studies: Investigating its role in appetite suppression, energy homeostasis, and as a potential target for obesity and diabetes research.
• Immunoassay Development: Used as a standard or antigen in the development and validation of ELISA and RIA kits for clinical diagnostics.
• Pharmaceutical R&D: Serving as a reference standard in drug discovery programs targeting Y4 receptors for metabolic and gastrointestinal indications.
• Cell Culture & In Vitro Studies: Application in cell-based assays to study receptor binding and downstream signaling pathways.
• Academic Research: A key reagent for university and institutional labs studying neuropeptides and their physiological effects.

Basic Information

Product Name	Pancreatic Polypeptide, Human
CAS No.	59763-91-6
Molecular Formula	C201H301N55O58S
Molecular Weight	4182.6 g/mol
Synonyms	Human Pancreatic Polypeptide; hPP; PPY; Pancreatic Polypeptide (1-36), human; PP; PYY; Pancreatic Propeptide; NPY; Neuropeptide Y Family Peptide; PP-fold Peptide
EINECS	Contact for details

Quality Control

Our Pancreatic Polypeptide, Human is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry for identity confirmation, and endotoxin testing to ensure it meets the stringent requirements for research use. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation. Aliquot reconstituted solutions to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Single Impurity (HPLC)	≤ 2.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.