Description

4-(n-Methyl-n-Nitrosamino)-4-(3-Pyridyl)Butane-1-Ol is a specialized nitrosamine compound featuring a pyridyl moiety, serving as a critical intermediate in advanced organic synthesis and analytical research. Its primary commercial value lies in its role as a reference standard and a key building block for the development of novel chemical entities and pharmaceutical candidates. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require precise and reliable synthetic intermediates for method development and quality control.

Application

• Pharmaceutical Reference Standard: Used for the identification, quantification, and method validation of nitrosamine impurities in active pharmaceutical ingredients (APIs) and finished drug products, ensuring compliance with stringent regulatory guidelines (e.g., FDA, EMA).
• Organic Synthesis Intermediate: Acts as a key precursor in the research and development of complex molecules, particularly those containing pyridine and nitrosamine functional groups for potential therapeutic applications.
• Analytical Research & Method Development: Employed in laboratories to develop and calibrate sensitive analytical techniques such as LC-MS/MS and GC-MS for trace-level nitrosamine analysis.
• Toxicological Studies: Serves as a standard compound in metabolic and genotoxicity studies to understand the biological impact and degradation pathways of nitrosamine derivatives.
• Agrochemical Research: Utilized in the synthesis of novel compounds for crop protection research, exploring new modes of action.
• Academic & Institutional Research: Provides a well-defined chemical for mechanistic studies in organic chemistry, medicinal chemistry, and environmental science.

Basic Information

Product Name	4-(n-Methyl-n-Nitrosamino)-4-(3-Pyridyl)Butane-1-Ol
CAS No.	59578-66-4
Molecular Formula	C10H15N3O2
Molecular Weight	209.25 g/mol
Synonyms	4-(Methylnitrosamino)-4-(3-pyridinyl)-1-butanol; 4-(N-Methyl-N-nitrosamino)-4-(3-pyridinyl)-1-butanol; 4-(3-Pyridyl)-4-(N-methyl-N-nitrosamino)-1-butanol; NNK Alcohol; 4-(Methylnitrosoamino)-1-(3-pyridyl)-1-butanol; 4-(N-Methyl-N-nitrosoamino)-4-(3-pyridyl)butan-1-ol; 4-(3-Pyridyl)-4-(methylnitrosamino)-1-butanol
EINECS	Contact for details

Quality Control

Every batch of 4-(n-Methyl-n-Nitrosamino)-4-(3-Pyridyl)Butane-1-Ol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to support its use as a high-purity reference material. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) or as specified on the label or COA. This compound is light-sensitive and easily oxidized; prolonged exposure to light, air, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.