Description

4-[[5-(1,2-Dithiolan-3-Yl)-1-Oxopentyl]Amino]Butanoic Acid is a specialized biochemical intermediate featuring a lipoic acid-derived structure conjugated with a butanoic acid moiety. This compound matters for its role as a key precursor in the synthesis of novel lipoamide analogs and enzyme cofactors, offering researchers a versatile building block for probing metabolic pathways. It is primarily needed by pharmaceutical R&D teams, academic biochemistry laboratories, and fine chemical manufacturers focused on developing advanced therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel lipoic acid derivatives and prodrugs targeting oxidative stress.
• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies related to dehydrogenase complexes and energy metabolism.
• Nutraceutical Development: Employed in the research and development of advanced antioxidant formulations and dietary supplements.
• Fine Chemical Synthesis: Acts as a versatile chiral building block for constructing complex molecules with potential bioactivity.
• Diagnostic Reagent Manufacturing: Utilized in the production of reagents and kits for metabolic disorder testing and research.

Basic Information

Product Name	4-[[5-(1,2-Dithiolan-3-Yl)-1-Oxopentyl]Amino]Butanoic Acid
CAS No.	59547-52-3
Molecular Formula	C12H21NO3S2
Molecular Weight	291.43 g/mol
Synonyms	4-[(5-(1,2-Dithiolan-3-yl)-1-oxopentyl)amino]butanoic acid; N-(4-Carboxybutyl)-6,8-dithiooctanamide; Lipoic acid butanoic acid conjugate; 6,8-Dithiooctanoic acid N-(4-carboxybutyl)amide; α-Lipoic acid-γ-aminobutyric acid conjugate; DL-α-Lipoamide-GABA derivative; 5-(1,2-Dithiolan-3-yl)-N-(4-carboxybutyl)pentanamide
EINECS	Contact for details

Quality Control

Our 4-[[5-(1,2-Dithiolan-3-Yl)-1-Oxopentyl]Amino]Butanoic Acid is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. All materials undergo comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP and ISO compliant manufacturing for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.