Description

1H-Indole, 5-Fluoro-2-Phenyl- is a high-value, fluorinated indole derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in its unique molecular scaffold, which combines the indole heterocycle with fluorine and phenyl substituents, enabling precise structural modifications for developing novel compounds. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the research and development of novel drug candidates, especially in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Acts as a precursor for functional organic materials, including organic light-emitting diodes (OLEDs) and conductive polymers.
• Academic & R&D Laboratories: Employed in medicinal chemistry and organic synthesis for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Serves as a specialized intermediate for custom synthesis and contract manufacturing of complex molecules.

Basic Information

Product Name	1H-Indole, 5-Fluoro-2-Phenyl-
CAS No.	59541-83-2
Molecular Formula	C₁₄H₁₀FN
Molecular Weight	211.24 g/mol
Synonyms	5-Fluoro-2-phenyl-1H-indole; 2-Phenyl-5-fluoroindole; 5-Fluoro-2-phenylindole; 5-Fluoro-2-phenyl-1H-indole; 2-(5-Fluorophenyl)indole (incorrect but common); 59541-83-2; 5-Fluoro-2-phenylindole
EINECS	Contact for details

Quality Control

Our 1H-Indole, 5-Fluoro-2-Phenyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.