Description

2-(tert-Butoxy)Acetonitrile is a versatile organic nitrile derivative characterized by its tert-butoxy functional group. This compound serves as a valuable protected glycolaldehyde nitrile equivalent and a key synthetic building block in advanced organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring protected aldehyde or cyanohydrin functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where its nitrile group acts as a reactive handle for further transformations.
• Ligand and Catalyst Development: Serves as a starting material for creating novel nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Manufacturing: Employed in the multistep synthesis of dyes, flavors, fragrances, and other high-value specialty chemicals.
• Academic and R&D Laboratories: A key reagent for methodological development in organic chemistry, including studies on nucleophilic addition, hydrolysis, and reduction reactions.
• Material Science Precursor: Potential use in the synthesis of monomers or functionalized polymers with specific chemical properties.

Basic Information

Product Name	2-(tert-Butoxy)Acetonitrile
CAS No.	59463-51-3
Molecular Formula	C6H11NO
Molecular Weight	113.16 g/mol
Synonyms	2-(tert-Butoxy)ethanenitrile; (tert-Butoxy)acetonitrile; Glycolonitrile tert-butyl ether; 2-tert-Butoxyacetonitrile; Acetonitrile, 2-(1,1-dimethylethoxy)-; 1-Cyano-2-tert-butoxyethane; tert-Butyl glycolonitrile ether
EINECS	Contact for details

Quality Control

Our 2-(tert-Butoxy)Acetonitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC/HPLC purity analysis and identity confirmation (IR, NMR), to ensure it meets the stringent requirements of research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.