Description

1-Stearoyl-2-Palmitoyl-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid with a defined fatty acid composition, serving as a critical building block for advanced lipid-based formulations. Its precisely controlled structure is essential for creating stable, reproducible, and biocompatible lipid bilayers, which are fundamental to modern pharmaceutical and biotechnological research. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, nutraceutical, and cosmetic industries for developing liposomal drug delivery systems, artificial membranes, and high-end lipid supplements.

Application

• Liposomal Drug Delivery Systems: A key component for formulating stable, long-circulating liposomes for targeted and sustained release of active pharmaceutical ingredients (APIs).
• Biomimetic Membrane Research: Used to create model cell membranes (e.g., supported lipid bilayers, vesicles) for studying membrane-protein interactions, permeability, and cellular processes.
• Cosmetic Formulations: Incorporated into high-performance skincare products like creams and serums for its emollient properties and ability to enhance skin barrier function and active ingredient delivery.
• Nutraceutical Encapsulation: Employed to encapsulate sensitive bioactive compounds (e.g., vitamins, antioxidants) in lipid nanoparticles to improve their stability, bioavailability, and absorption.
• Diagnostic Reagents: Utilized in the production of reagents for diagnostic assays that require specific lipid environments or as a component of calibration standards.
• Cell Culture & Biotechnology: Acts as a lipid supplement in serum-free cell culture media or as a raw material for synthesizing more complex lipid conjugates.

Basic Information

Product Name	1-Stearoyl-2-Palmitoyl-Sn-Glycero-3-Phosphocholine
CAS No.	59403-53-1
Molecular Formula	C43H86NO8P
Molecular Weight	776.11 g/mol
Synonyms	SPPC; 18:0-16:0 PC; 1-Stearoyl-2-palmitoylphosphatidylcholine; 1-Octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine; Phosphatidylcholine (18:0/16:0); (2R)-2,3-Bis(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate; 1-Stearoyl-2-palmitoyl-sn-glycerol-3-phosphorylcholine; Palmitoyl Stearoyl Phosphatidylcholine
EINECS	Contact for details

Quality Control

Our 1-Stearoyl-2-Palmitoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and fatty acid composition, NMR for structural confirmation, and tests for residual solvents and heavy metals. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Complies
Assay (HPLC)	≥ 98.0%
Fatty Acid Composition (GC)	Stearic Acid (C18:0): ~50% Palmitic Acid (C16:0): ~50%
Loss on Drying	≤ 2.0 %
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.