Description

(4-Methylumbelliferyl)-n-Acetyl-4,7,8,9-Tetra-o-Acetyl-A-D-Neuraminic Acid, Methyl Ester is a specialized fluorogenic substrate and a key synthetic intermediate in glycobiology research. This compound is critical for the sensitive detection and kinetic analysis of neuraminidase (sialidase) enzyme activity. It is primarily utilized by researchers and manufacturers in the pharmaceutical, diagnostic, and life science sectors for developing enzyme assays and studying carbohydrate-active enzymes.

Application

• Neuraminidase (Sialidase) Activity Assays: Acts as a fluorogenic substrate for the sensitive, continuous monitoring of enzyme kinetics in research and high-throughput screening.
• Diagnostic Reagent Development: Used in the formulation of diagnostic kits for detecting bacterial or viral neuraminidases.
• Glycobiology Research: Serves as a crucial tool for studying sialic acid metabolism, enzyme inhibition, and the role of sialidases in disease pathways.
• Pharmaceutical R&D: Employed in the discovery and characterization of novel neuraminidase inhibitors for therapeutic applications.
• Biochemical Substrate: Provides a standardized, high-purity substrate for quality control and assay validation in academic and industrial laboratories.

Basic Information

Item	Details
Product Name	(4-Methylumbelliferyl)-n-Acetyl-4,7,8,9-Tetra-o-Acetyl-A-D-Neuraminic Acid, Methyl Ester
CAS No.	59361-08-9
Molecular Formula	C31H38N2O17
Molecular Weight	710.64 g/mol
Synonyms	4-MU-Neu5Ac4,7,8,9-tetra-O-acetyl-α-methylglycoside; 4-Methylumbelliferyl-5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-non-2-ulopyranosidonic acid methyl ester 4,7,8,9-tetraacetate; MU-α-Neu5Ac4,7,8,9-tetra-OAc-Me; Fluorogenic Neuraminidase Substrate; 4-MU-α-Neu5Ac4,7,8,9-Tetra-O-Ac-Me; Neuraminidase Fluorogenic Substrate
EINECS	Contact for details

Quality Control

Every batch of our (4-Methylumbelliferyl)-n-Acetyl-4,7,8,9-Tetra-o-Acetyl-A-D-Neuraminic Acid, Methyl Ester is produced and tested under strict quality management systems. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.