Description

2,2,4-Trimethyl-3-Hydroxy-n-Valeronitrile is a versatile nitrile derivative with a hydroxyl functional group, making it a valuable chiral building block and intermediate in organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the synthesis of pharmaceuticals and fine chemicals where precise stereochemistry is critical. Industries that need it include pharmaceutical R&D, agrochemical manufacturing, and specialty chemical producers focused on developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of active pharmaceutical ingredients (APIs), especially in routes requiring β-hydroxy nitrile motifs.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and plant growth regulators with specific stereochemical properties.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, fragrances, and performance materials.
• Asymmetric Synthesis: Serves as a precursor in catalytic asymmetric reactions to introduce chiral centers into target molecules.
• Polymer Modification: Potential monomer or modifier for specialty polymers and resins, contributing to specific material properties.
• Research & Development: Valuable reference standard and starting material in academic and industrial organic chemistry laboratories.

Basic Information

Item	Details
Product Name	2,2,4-Trimethyl-3-Hydroxy-n-Valeronitrile
CAS No.	59346-56-4
Molecular Formula	C8H15NO
Molecular Weight	141.21 g/mol
Synonyms	3-Hydroxy-2,2,4-trimethylpentanenitrile; 2,2,4-Trimethyl-3-hydroxypentanenitrile; 3-Hydroxy-2,2,4-trimethylvaleronitrile; β-Hydroxy nitrile derivative; TMHVN; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2,2,4-Trimethyl-3-Hydroxy-n-Valeronitrile is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, impurities, and physical parameters are provided and available upon request, supporting compliance in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. Due to the presence of functional groups sensitive to hydrolysis and oxidation, consider storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.