Description

4'-Chloro-2'-Fluoroacetanilide is a high-purity, versatile organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its role as a key building block for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research and development chemists, process engineers, and manufacturers requiring a reliable and consistent raw material for producing active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various active pharmaceutical ingredients (APIs), especially those containing halogenated aniline motifs.
• Agrochemical Synthesis: Used in the manufacturing of advanced herbicides, fungicides, and insecticides where the chloro-fluoro substitution pattern is required for bioactivity.
• Organic Synthesis Building Block: Serves as a versatile starting material or intermediate in complex organic reactions, including cross-coupling and amide bond formation.
• Dye and Pigment Manufacturing: Employed in the production of specialized dyes and pigments that require halogenated aniline derivatives for color fastness and specific properties.
• Research & Development: A valuable compound for medicinal chemistry and process chemistry research in academic and industrial laboratories.
• Fine Chemical Production: Integral to the synthesis of other fine chemicals and custom organic molecules for various industrial applications.

Basic Information

Product Name	4'-Chloro-2'-Fluoroacetanilide
CAS No.	59280-70-5
Molecular Formula	C8H7ClFNO
Molecular Weight	187.60 g/mol
Synonyms	N-(4-Chloro-2-fluorophenyl)acetamide; 2-Fluoro-4-chloroacetanilide; 1-Acetamido-4-chloro-2-fluorobenzene; Acetamide, N-(4-chloro-2-fluorophenyl)-; 4-Chloro-2-fluoro-N-phenacylacetamide; 4-Chloro-2-fluoroacetanilide; N-Acetyl-4-chloro-2-fluoroaniline
EINECS	Contact for details

Quality Control

Our 4'-Chloro-2'-Fluoroacetanilide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure it meets the highest standards of purity and consistency required for sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee full traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.