Description

1,1-Difluoro-2-Methoxy-Cyclopropane is a specialized fluorinated cyclopropane derivative, serving as a valuable building block in advanced organic synthesis. Its unique structure, featuring both fluorine atoms and a methoxy group on a strained three-membered ring, makes it a versatile precursor for introducing fluorinated moieties into complex molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for incorporating fluorinated cyclopropane motifs known to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorinated cyclopropane structure can contribute to improved efficacy and environmental profile.
• Material Science Research: Employed as a monomer or precursor in the development of novel fluorinated polymers and specialty materials with unique surface properties.
• Organic Synthesis Building Block: Serves as a versatile reagent in academic and industrial laboratories for ring-opening reactions, cross-coupling, and other transformations to construct complex molecular architectures.
• Ligand and Catalyst Development: Utilized in the synthesis of novel fluorinated ligands for catalysis and molecular recognition applications.

Basic Information

Product Name	1,1-Difluoro-2-Methoxy-Cyclopropane
CAS No.	59164-22-6
Molecular Formula	C5H8F2O
Molecular Weight	122.11 g/mol
Synonyms	2-Methoxy-1,1-difluorocyclopropane; 1,1-Difluoro-2-methoxycyclopropane; Difluoromethoxycyclopropane; Cyclopropane, 1,1-difluoro-2-methoxy-; 59164-22-6
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fluorinated intermediates. Production follows current Good Manufacturing Practice (cGMP) principles where applicable, and each batch is analyzed to ensure it meets precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the potential sensitivity of fluorinated cyclopropanes, it is recommended to store under an inert atmosphere for long-term stability and to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.