Description

2',4'-Difluoro[1,1'-Biphenyl]-4-Yl Acetate is a high-purity fluorinated biphenyl derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile aromatic scaffold with fluorine atoms that can dramatically influence the electronic properties and metabolic stability of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in oncology and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the difluorobiphenyl core enhances bioactivity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display materials, contributing to improved stability and performance.
• Organic Ligand Synthesis: Employed in creating specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Polymer Science: Incorporated as a monomer or modifier to impart specific thermal and chemical resistance properties to high-performance polymers.
• Chemical Research & Development: Serves as a versatile substrate for method development in cross-coupling reactions and fluorination chemistry.

Basic Information

Product Name	2',4'-Difluoro[1,1'-Biphenyl]-4-Yl Acetate
CAS No.	59089-67-7
Molecular Formula	C14H10F2O2
Molecular Weight	248.22 g/mol
Synonyms	4'-Acetoxy-2,4-difluorobiphenyl; [1,1'-Biphenyl]-4-ol, 2',4'-difluoro-, acetate; 2',4'-Difluorobiphenyl-4-yl acetate; 4-(2,4-Difluorophenyl)phenyl acetate; (2',4'-Difluoro[1,1'-biphenyl]-4-yl) acetate; Acetic acid 2',4'-difluorobiphenyl-4-yl ester
EINECS	Contact for details

Quality Control

Every batch of 2',4'-Difluoro[1,1'-Biphenyl]-4-Yl Acetate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets a typical purity specification of ≥97% (HPLC), with higher purity grades available. Comprehensive Certificates of Analysis (COA) detailing assay, impurity profile, and physical characteristics are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.