Description

2-Fluoro-6-Iodonaphthalene is a high-purity, halogenated naphthalene derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting central nervous system and oncological diseases.
• Agrochemical Research: Used in developing new generation herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a core building block for electron-transport materials, host materials, and other functional components in display and lighting technologies.
• Cross-Coupling Reactions: The iodine moiety acts as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form new carbon-carbon bonds.
• Fluorine Chemistry Research: A valuable substrate for studying fluorine-directed ortho-metalation and other regioselective functionalization reactions.
• Ligand Synthesis: Intermediate for creating specialized fluorinated ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	2-Fluoro-6-Iodonaphthalene
CAS No.	59079-75-3
Molecular Formula	C₁₀H₆FI
Molecular Weight	272.06 g/mol
Synonyms	2-Fluoro-6-iodonaphthalene; 6-Iodo-2-fluoronaphthalene; Naphthalene, 2-fluoro-6-iodo-; 2-Fluoronaphthalene-6-iodide; 2-F-6-I-Naphthalene; 2-Fluoro-6-iodo-naphthalene; 2-Fluoro-6-iodanyl-naphthalene
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Iodonaphthalene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications in cGMP environments and advanced research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Heavy Metals	<10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.