Description

N,N'-Hexane-1,6-Diylbis[3-Amino-2-Butenamide] is a specialized diamide derivative with a defined linear hexamethylene spacer, offering a unique bifunctional reactive platform. This compound is valued for its ability to act as a versatile linker or cross-linking agent in advanced material synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process engineers in the fine chemical, polymer, and life science sectors for developing novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, particularly those requiring a specific chain length and amide functionality.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of polyamides, polyurethanes, and other specialty polymers to modify thermal and mechanical properties.
• Bioconjugation & Linker Chemistry: Used in the development of antibody-drug conjugates (ADCs) and other bioconjugates, where its amino and amide groups facilitate stable linkages between biomolecules and payloads.
• Material Science Research: Employed in creating novel organic frameworks, dendrimers, and surface modifiers for coatings and composites.
• Agrochemical Synthesis: Functions as an intermediate in the design and production of new-generation herbicides and plant growth regulators.
• Cosmetic Ingredient Intermediate: Used in the synthesis of film-forming agents, conditioners, and other functional additives for personal care formulations.

Basic Information

Product Name	N,N'-Hexane-1,6-Diylbis[3-Amino-2-Butenamide]
CAS No.	58977-86-9
Molecular Formula	C16H28N4O2
Molecular Weight	308.42 g/mol
Synonyms	1,6-Hexanediamine, N,N'-bis(3-amino-2-butenoyl)-; 3-Amino-2-butenamide, N,N'-1,6-hexanediylbis-; N,N'-Bis(3-aminocrotonoyl)-1,6-hexanediamine; 1,6-Bis(3-amino-2-butenamido)hexane; Hexamethylene bis(3-aminocrotonamide); N1,N6-Bis(3-aminobut-2-enoyl)hexane-1,6-diamine
EINECS	Contact for details

Quality Control

Our N,N'-Hexane-1,6-Diylbis[3-Amino-2-Butenamide] is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.