Description

H-Val-Pro-Pro-Oh CAS NO 58872-39-2 is a high-purity tripeptide, specifically the C-terminal amide derivative of the well-known bioactive peptide Val-Pro-Pro. This compound serves as a critical pharmaceutical intermediate and research-grade biochemical for advanced studies in enzymology and peptide chemistry. It is essential for manufacturers and researchers in the pharmaceutical, nutraceutical, and life science research sectors requiring precise and reliable peptide building blocks.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Serves as a reference standard, substrate, or inhibitor in enzymatic studies, particularly those involving angiotensin-converting enzyme (ACE).
• Nutraceutical Development: A key component in the research and development of functional food ingredients and dietary supplements targeting cardiovascular health.
• Peptide Library Synthesis: Employed as a building block in combinatorial chemistry for creating diverse peptide libraries for screening.
• Academic & Industrial R&D: Fundamental material for investigating structure-activity relationships (SAR) and metabolic pathways of bioactive peptides.

Basic Information

Product Name	H-Val-Pro-Pro-Oh
CAS No.	58872-39-2
Molecular Formula	C16H27N3O4
Molecular Weight	325.40 g/mol
Synonyms	Val-Pro-Pro amide; L-Valyl-L-prolyl-L-prolinamide; VPP-NH2; ACE Inhibitory Tripeptide Amide; N-(N-L-Valyl-L-prolyl)-L-prolinamide; H-Val-Pro-Pro-NH2; 2-[(2S)-1-[(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]pyrrolidin-1-yl]-1-oxopropan-2-yl]pyrrolidine-1-carboxamide
EINECS	Contact for details

Quality Control

Our H-Val-Pro-Pro-Oh is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets stringent specifications for research and production use. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 98.5%
Single Impurity (HPLC)	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.