Description

Zymosan A is a purified polysaccharide derived from yeast cell walls, widely recognized for its potent immunostimulatory properties. This high-purity biological reagent is essential for research and development in immunology and inflammation studies. It serves as a critical tool for scientists and manufacturers in the pharmaceutical, biotechnology, and life science research sectors, enabling the study of innate immune responses and macrophage activation.

Application

• Immunological Research: Used as a standard ligand to stimulate Toll-like receptor 2 (TLR2) signaling and study innate immune responses.
• Inflammation Models: Employed to induce experimental peritonitis, arthritis, and other inflammatory conditions in animal models for drug discovery.
• Macrophage Activation: A key reagent for activating macrophages and dendritic cells in vitro to study cytokine production and phagocytosis.
• Complement System Studies: Utilized to activate the alternative complement pathway in biochemical assays.
• Vaccine Adjuvant Research: Investigated for its potential as an immune potentiator in adjuvant formulation development.
• Biomaterial & Diagnostic Development: Used in the development of biosensors and diagnostic kits that detect immune system activity.

Basic Information

Product Name	Zymosan A
CAS No.	58856-93-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Zymosan; Zymosan A from Saccharomyces cerevisiae; Yeast Cell Wall Polysaccharide; Glucan from Yeast; TLR2 Agonist; (1→3)-β-D-Glucan; Zymosan A Bioparticles; Complement Activator Zymosan
EINECS	Contact for details

Quality Control

Our Zymosan A is produced under stringent quality management systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including purity assessment, biological activity verification, and endotoxin level checks. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our rigorous in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation. For long-term stability, consider storage under desiccant.

Specification

Item	Specification
Appearance	Off-white to light tan powder
Identification (IR)	Conforms to reference spectrum
Assay (β-Glucan Content)	≥ 95%
Protein Content	≤ 1.0%
Endotoxin Level	< 10 EU/mg
Loss on Drying	≤ 5.0%
Biological Activity	Stimulates TNF-α release in standard macrophage assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.