Description

Ethanone, 2-Chloro-2-Fluoro-1-(1H-Indol-3-Yl)- (9Ci) is a specialized fluorinated indole derivative, a high-value intermediate in advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated structure enables precise molecular modifications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce fluorinated motifs into complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in developing novel herbicides and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Chemical Biology Probe: Serves as a precursor for fluorescent tags or molecular probes used in biochemical and cellular imaging studies.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploratory synthesis of new chemical entities.

Basic Information

Product Name	Ethanone, 2-Chloro-2-Fluoro-1-(1H-Indol-3-Yl)- (9Ci)
CAS No.	58750-64-4
Molecular Formula	C10H7ClFNO
Molecular Weight	211.62 g/mol
Synonyms	2-Chloro-2-fluoro-1-(1H-indol-3-yl)ethanone; 3-(2-Chloro-2-fluoroacetyl)indole; 2-Chloro-2-fluoro-1-(indol-3-yl)ethan-1-one; 1H-Indole-3-acetyl chloride, 2-fluoro-; 58750-64-4; 2-Chloro-2-fluoro-3-indolyl ethanone; 3-Acetylindole, 2-chloro-2-fluoro-; 2-Fluoro-2-chloro-1-(1H-indol-3-yl)ethanone
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Each batch of Ethanone, 2-Chloro-2-Fluoro-1-(1H-Indol-3-Yl)- (9Ci) is analyzed using advanced techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality system supports development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.