Description

n-Cyclohexylglycine is a non-proteinogenic amino acid derivative featuring a cyclohexyl substituent, offering unique steric and lipophilic properties. This compound is a versatile chiral building block crucial for the synthesis of complex molecules where conformational rigidity and enhanced bioavailability are desired. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from peptide mimetics to catalyst ligands.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for introducing constrained peptide backbones.
• Peptidomimetics Research: Used to create conformationally restricted analogs of natural peptides to enhance metabolic stability and receptor selectivity.
• Agrochemical Synthesis: Acts as a building block for designing new herbicides and fungicides with improved efficacy and environmental profiles.
• Catalyst & Ligand Design: Employed in the development of asymmetric catalysts and chiral ligands for stereoselective synthesis.
• Biochemical Research: Utilized as a substrate or inhibitor in enzymatic studies to probe active site specificity and function.
• Specialty Polymers: Incorporated into polymer chains to modify physical properties such as solubility, thermal stability, and rigidity.

Basic Information

Product Name	n-Cyclohexylglycine
CAS No.	58695-41-3
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	2-(Cyclohexylamino)acetic acid; Cyclohexylglycine; (Cyclohexylamino)acetic acid; NSC 163063; Glycine, N-cyclohexyl-; α-(Cyclohexylamino)acetic acid; Amino(cyclohexyl)acetic acid
EINECS	Contact for details

Quality Control

Our n-Cyclohexylglycine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.