Description

4-(Trifluoromethyl)Cyclohexanamine is a versatile fluorinated amine building block characterized by its cyclohexyl backbone and electron-withdrawing trifluoromethyl group. This compound is highly valued for its ability to impart unique physicochemical properties, such as enhanced metabolic stability and lipophilicity, to advanced molecular architectures. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry for creating molecules with improved bioavailability and target selectivity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated to modify the properties of specialty polymers, imparting characteristics like chemical resistance or altered surface energy.
• Catalyst Ligand Precursor: Utilized in the synthesis of chiral or specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Organic Synthesis Building Block: Employed in general organic synthesis for introducing the amine and trifluoromethyl motifs into more complex molecules via amidation, reductive amination, or other coupling reactions.

Basic Information

Product Name	4-(Trifluoromethyl)Cyclohexanamine
CAS No.	58665-70-6
Molecular Formula	C7H12F3N
Molecular Weight	167.17 g/mol
Synonyms	4-(Trifluoromethyl)cyclohexanamine; 4-(Trifluoromethyl)cyclohexylamine; trans-4-(Trifluoromethyl)cyclohexanamine; cis-4-(Trifluoromethyl)cyclohexanamine; 4-Aminomethyl-α,α,α-trifluorotoluene (cyclic); 4-Cyclohexylamine, trifluoromethyl-; 4-Trifluoromethyl-1-cyclohexanamine; 1-Cyclohexanamine, 4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Cyclohexanamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with REACH and other global regulatory frameworks for industrial chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (typical grade)
Water Content (KF)	≤ 0.5%
Isomer Ratio (cis/trans)	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.