Description

Carbon-11 Methionine is a positron-emitting radiopharmaceutical compound, synthesized by incorporating the radioactive isotope Carbon-11 into the methionine amino acid structure. This product is essential for non-invasive diagnostic imaging using Positron Emission Tomography (PET), enabling the visualization and quantification of metabolic processes in vivo. It is primarily utilized by research institutions, pharmaceutical companies, and advanced medical imaging centers for oncology and neurology research, particularly in studying tumor proliferation and amino acid transport mechanisms.

Application

• Oncology PET Imaging: Used as a tracer for detecting and monitoring tumor metabolism, especially in brain tumors, prostate cancer, and other malignancies with high amino acid uptake.
• Neurological Research: Facilitates the study of protein synthesis rates, neurotransmitter pathways, and the pathophysiology of disorders like epilepsy and Alzheimer's disease.
• Drug Development: Serves as a critical tool in preclinical and clinical trials for evaluating the efficacy of new therapeutic agents targeting cancer metabolism.
• Radiosynthesis Reference: Acts as a key starting material or reference standard in the synthesis and quality control of other Carbon-11 labeled compounds.

Basic Information

Product Name	Carbon-11 Methionine
CAS No.	58576-49-1
Molecular Formula	C11H11NO2S
Molecular Weight	Contact for details
Synonyms	L-[11C]Methionine; [11C]Methionine; Carbon-11 L-Methionine; 11C-Met; (2S)-2-Amino-4-([11C]methylsulfanyl)butanoic acid; S-([11C]Methyl)-L-cysteine; PET Tracer Methionine C-11
EINECS	Contact for details

Quality Control

Every batch of Carbon-11 Methionine is produced and tested under strict cGMP conditions to ensure the highest standards of radiochemical purity, sterility, and apyrogenicity. Quality assurance includes rigorous analytical testing via HPLC and TLC to confirm identity, specific activity, and radiochemical purity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all release specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its radioactive nature and high volatility, the product must be stored appropriately immediately after synthesis and used within its very short half-life (approximately 20.4 minutes). Specific storage and handling protocols are provided with the technical data sheet.

Specification

Item	Specification
Appearance	Clear, colorless solution
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	Contact for details
Specific Activity	Contact for details
pH	4.5 - 7.5
Sterility Test	Sterile
Bacterial Endotoxins	< 175 EU/V
Radionuclidic Identity (Half-life)	20.4 min (± 10%)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.