Description

Benzonitrile, 4-Chloro-2,5-Dihydroxy- is a specialized chlorinated dihydroxybenzonitrile derivative, a key synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the synthesis of active pharmaceutical ingredients (APIs) and high-performance agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific chlorinated phenolic functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides and fungicides, where the chlorinated dihydroxy structure contributes to biological activity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal catalysis and coordination chemistry due to its phenolic and nitrile functional groups.
• Polymer Chemistry: Acts as a monomer or modifier in the production of high-performance polymers, such as polyesters and polyamides, with enhanced thermal or chemical resistance.
• Dye and Pigment Manufacturing: Employed as an intermediate in the synthesis of complex organic dyes and pigments, contributing to color fastness and stability.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new organic reactions and synthesizing complex heterocyclic compounds.

Basic Information

Product Name	Benzonitrile, 4-Chloro-2,5-Dihydroxy-
CAS No.	58543-90-1
Molecular Formula	C7H4ClNO2
Molecular Weight	169.56 g/mol
Synonyms	4-Chloro-2,5-dihydroxybenzonitrile; 2,5-Dihydroxy-4-chlorobenzonitrile; 4-Chloro-2,5-dihydroxybenzenecarbonitrile; 4-Chloro-2,5-dihydroxybenzene carbonitrile; 4-Chloro-2,5-dihydroxy-phenyl cyanide; 4-Chloro-2,5-dihydroxybenzonitrile (CAS 58543-90-1); 4-Chloro-2,5-dihydroxy cyanobenzene
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,5-dihydroxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and oxidation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.