Description

Boc-3-(2-Naphthyl)-L-Alanine is a protected amino acid derivative, specifically an N-Boc-protected L-amino acid with a bulky 2-naphthyl side chain. This compound is a crucial chiral building block in the synthesis of complex peptides and peptidomimetics, offering high stereochemical purity for demanding research and development. It is primarily utilized by pharmaceutical researchers, peptide chemists, and fine chemical manufacturers working on drug discovery, bioactive peptide synthesis, and advanced material science.

Application

• Pharmaceutical Intermediates: Key chiral synthon for the development of novel therapeutic peptides and protease inhibitors.
• Peptide Synthesis (Solid-Phase & Solution-Phase): Used as a protected amino acid residue to introduce the hydrophobic 2-naphthylalanine moiety into peptide sequences.
• Drug Discovery & Medicinal Chemistry: Serves as a building block for creating focused libraries and structure-activity relationship (SAR) studies.
• Bioconjugation & Labeling: The reactive carboxyl and protected amine groups allow for site-specific modifications in bioconjugate chemistry.
• Academic & Industrial R&D: Essential for research in peptide science, asymmetric synthesis, and molecular recognition studies.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialized, high-value organic compounds.

Basic Information

Item	Details
Product Name	Boc-3-(2-Naphthyl)-L-Alanine
CAS No.	58438-04-3
Molecular Formula	C₁₈H₂₁NO₄
Molecular Weight	315.36 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-L-alanine; Boc-2-Nal-OH; Boc-L-2-Naphthylalanine; (S)-2-((tert-Butoxycarbonyl)amino)-3-(naphthalen-2-yl)propanoic acid; N-Boc-3-(2-naphthyl)-L-alanine; tert-Butyloxycarbonyl-2-naphthyl-L-alanine; Boc-2-Naphthyl-L-Ala-OH; Boc-L-β-(2-Naphthyl)-alanine
EINECS	Contact for details

Quality Control

Our Boc-3-(2-Naphthyl)-L-Alanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and fine chemical synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.