Description

(S)-Benzyl 2-Carbamoylpyrrolidine-1-Carboxylate is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key precursor for the construction of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the synthesis of proline-based drug candidates, including protease inhibitors and other bioactive molecules.
• Peptidomimetics Research: Serves as a constrained proline analog for designing and synthesizing novel peptidomimetics with enhanced metabolic stability and receptor selectivity.
• Asymmetric Catalysis: Used as a precursor for chiral ligands or organocatalysts in stereoselective synthesis.
• Agrochemical Synthesis: Employed in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research programs.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	(S)-Benzyl 2-Carbamoylpyrrolidine-1-Carboxylate
CAS No.	58274-22-9
Molecular Formula	C13H16N2O3
Molecular Weight	248.28 g/mol
Synonyms	(S)-1-(Benzyloxycarbonyl)-2-carbamoylpyrrolidine; (S)-1-CBZ-2-Carbamoylpyrrolidine; (S)-N-Cbz-2-Carbamoylpyrrolidine; (S)-1-Benzyloxycarbonyl-2-aminocarbonylpyrrolidine; (S)-2-Carbamoyl-1-[(benzyloxy)carbonyl]pyrrolidine; (S)-1-(Benzyloxycarbonyl)pyrrolidine-2-carboxamide; (S)-Pyrrolidine-2-carboxamide, 1-[(benzyloxy)carbonyl]-; (S)-Prolineamide, N-benzyloxycarbonyl-
EINECS	Contact for details

Quality Control

Our (S)-Benzyl 2-Carbamoylpyrrolidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.