Description

5-(Acetylamino)-3-(β-D-Glucopyranosyloxy)-n-Methyl-2,4,6-Triiodobenzamide CAS NO 58199-95-4 is a specialized iodinated organic compound primarily used as a key intermediate in the synthesis of X-ray contrast media. This high-purity chemical is critical for ensuring the safety and efficacy of diagnostic imaging agents. It is essential for pharmaceutical manufacturers and advanced research institutions developing next-generation non-ionic, low-osmolar contrast media.

Application

• Pharmaceutical Intermediate: Primary building block for the synthesis of iopamidol and related non-ionic X-ray contrast agents.
• Diagnostic Imaging Research: Used in R&D for developing novel iodinated contrast media with improved safety profiles.
• Active Pharmaceutical Ingredient (API) Synthesis: A critical precursor in multi-step GMP manufacturing processes for contrast agents.
• Biomedical Research: Serves as a model compound in studies investigating the pharmacokinetics and metabolism of iodinated molecules.
• Quality Control Reference Standard: Used as a high-purity reference material for analytical method development and validation in QC laboratories.

Basic Information

Product Name	5-(Acetylamino)-3-(β-D-Glucopyranosyloxy)-n-Methyl-2,4,6-Triiodobenzamide
CAS No.	58199-95-4
Molecular Formula	C16H20I3N3O7
Molecular Weight	787.06 g/mol
Synonyms	5-Acetamido-3-(β-D-glucopyranosyloxy)-N-methyl-2,4,6-triiodobenzamide; Iopamidol Intermediate; 5-Acetylamino-3-(β-D-glucopyranosyloxy)-N-methyl-2,4,6-triiodobenzamide; Iopamidol Precursor; 58199-95-4; 3-(β-D-Glucopyranosyloxy)-5-(acetylamino)-N-methyl-2,4,6-triiodobenzamide; Benzamide, 5-(acetylamino)-3-(β-D-glucopyranosyloxy)-N-methyl-2,4,6-triiodo-
EINECS	Contact for details

Quality Control

Our 5-(Acetylamino)-3-(β-D-Glucopyranosyloxy)-n-Methyl-2,4,6-Triiodobenzamide is manufactured under strict quality systems suitable for pharmaceutical intermediate applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Quality is assured through rigorous analytical testing, including HPLC, IR, and residual solvent analysis, aligning with ICH guidelines. Specifications can be tailored to meet specific GMP or research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C limits
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.