Description

n-Ethyl-2,2,2-trifluoroethanamine is a versatile fluorinated amine building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of an ethylamino group and a trifluoroethyl moiety, which imparts desirable properties like altered lipophilicity and metabolic stability to target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for introducing the trifluoroethylamine group into drug candidates, potentially enhancing bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where fluorine substitution is critical for activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of fluorinated polymers, surfactants, or specialty materials with unique surface properties.
• Organic Synthesis Building Block: A valuable reagent for constructing complex molecules in academic and industrial research settings.

Basic Information

Product Name	n-Ethyl-2,2,2-Trifluoroethanamine
CAS No.	58171-47-4
Molecular Formula	C4H8F3N
Molecular Weight	127.11 g/mol
Synonyms	2,2,2-Trifluoro-N-ethylethanamine; N-Ethyl-2,2,2-trifluoroethylamine; 2,2,2-Trifluoroethylamine, N-ethyl-; 1,1,1-Trifluoro-2-(ethylamino)ethane; N-Ethyltrifluoroethylamine; TFEA; Ethyl(2,2,2-trifluoroethyl)amine
EINECS	Contact for details

Quality Control

Our n-Ethyl-2,2,2-trifluoroethanamine is produced under stringent quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids and oxidizing agents. Due to its fluoride/strong alkali nature, handle with appropriate precautions to avoid moisture ingress and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.