Description

Iopanoate Glucuronide is a key metabolite and reference standard of the iodinated contrast agent iopanoic acid. This compound is essential for analytical research and quality control in the development and manufacturing of diagnostic imaging agents. It is primarily used by pharmaceutical R&D laboratories, analytical service providers, and manufacturers of contrast media for method development, validation, and impurity profiling.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for the quantification and identification of iopanoic acid and its metabolites in biological matrices and pharmaceutical formulations.
• Metabolite Studies: Critical for in vitro and in vivo ADME (Absorption, Distribution, Metabolism, and Excretion) studies to understand the metabolic pathway of iopanoic acid.
• Analytical Method Development: Used to develop and validate high-performance liquid chromatography (HPLC), LC-MS/MS, and other chromatographic methods for impurity analysis and assay.
• Quality Control (QC) Testing: Employed in the QC laboratories of contrast media manufacturers to ensure batch-to-batch consistency and to monitor for specific glucuronidated impurities.
• Clinical Research: Supports bioanalytical studies in clinical trials involving iodinated contrast agents to assess pharmacokinetics and safety profiles.

Basic Information

Product Name	Iopanoate Glucuronide
CAS No.	58051-18-6
Molecular Formula	C20H24I3NO9
Molecular Weight	827.02 g/mol
Synonyms	Iopanoic Acid Glucuronide; 3-[[(3-Amino-2,4,6-triiodophenyl)methyl]amino]-2-methylpropanoic Acid Glucuronide; Glucuronide of Iopanoic Acid; Iopanoic Acid β-D-Glucuronide; Telepaque Glucuronide; 1-O-(Iopanoate)-β-D-Glucopyranuronic Acid
EINECS	Contact for details

Quality Control

Our Iopanoate Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for reference material applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single unknown impurity ≤ 1.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.