Description

(Z)-4-[3-(2-Chloro-9H-Thioxanthen-9-Ylidene)Propyl]Piperazine-1-Ethanol Dihydrochloride is a high-purity, synthetic organic compound belonging to the thioxanthene chemical class. This compound is of significant interest for its role as a key intermediate in advanced pharmaceutical research and development. It is primarily utilized by pharmaceutical manufacturers and R&D laboratories engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targeting drugs.
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new drug candidates with potential antipsychotic or neuroleptic activity.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Chemical Synthesis: Employed in organic synthesis to introduce the thioxanthene-piperazine pharmacophore into more complex molecular structures.

Basic Information

Item	Details
Product Name	(Z)-4-[3-(2-Chloro-9H-Thioxanthen-9-Ylidene)Propyl]Piperazine-1-Ethanol Dihydrochloride
CAS No.	58045-23-1
Molecular Formula	C22H26Cl3N2OS
Molecular Weight	481.87 g/mol
Synonyms	Zuclopenthixol Impurity; (Z)-Clopenthixol Dihydrochloride; (Z)-4-[3-(2-Chloro-9H-Thioxanthen-9-Ylidene)Propyl]-1-piperazineethanol Dihydrochloride; cis-Zuclopenthixol Dihydrochloride; (Z)-Clopenthixol 2HCl; 2-Chloro-9-[3-[(4-(2-hydroxyethyl)-1-piperazinyl]propylidene]thioxanthene Dihydrochloride; (Z)-Clopenthixol Hydrochloride
EINECS	Contact for details

Quality Control

Our (Z)-4-[3-(2-Chloro-9H-Thioxanthen-9-Ylidene)Propyl]Piperazine-1-Ethanol Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets stringent specifications for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.